Acute Myocardial Infarction
Definition
Myocardial infarction (MI) is irreversible necrosis of heart muscle
secondary to prolonged ischemia
It results from an imbalance of oxygen supply and demand
The appearance of cardiac enzymes in the circulation generally
indicates myocardial necrosis
MI is considered part of a spectrum referred to as acute coronary
syndromes (ACSs), which also includes unstable angina and non–Q-
wave MI (NQWMI)
Patients with ischemic discomfort may or may not have ST-
segment elevation
The majority of those with ST-segment elevation will develop Q
waves
Those without ST elevation ultimately will be diagnosed with
unstable angina or NQWMI on the basis of the presence of cardiac
enzymes
MI may lead to impairment of systolic or diastolic function and to
increased predisposition to arrhythmias and other long-term
complications
Definition
Myocardial infarction (MI) is irreversible necrosis of heart muscle
secondary to prolonged ischemia
It results from an imbalance of oxygen supply and demand
The appearance of cardiac enzymes in the circulation generally
indicates myocardial necrosis
MI is considered part of a spectrum referred to as acute coronary
syndromes (ACSs), which also includes unstable angina and non–Q-
wave MI (NQWMI)
Patients with ischemic discomfort may or may not have ST-
segment elevation
The majority of those with ST-segment elevation will develop Q
waves
Those without ST elevation ultimately will be diagnosed with
unstable angina or NQWMI on the basis of the presence of cardiac
enzymes
MI may lead to impairment of systolic or diastolic function and to
increased predisposition to arrhythmias and other long-term
complications
Cardiovascular Diseases
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| Acute Myocardial Infarction |